Chlamydiae

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Questions:

Q. Why are chlamydiae Obligate intracellular parasites?

Q. What are 2 forms of Chlamydiae?

Q. What is peculiar about Chlamydial cell wall?

Q. How can chlamydiae be diagnosed in lab?

Q. What diseases are Caused by C. trachomatis?

Q. What diseases are casued by C. pneumonia and C. pisttaci?

Q. How is Chlamydial infection treated?

Q. What dieases are caused by Serotypes A, B & C?

Q. What diseases are caused by Serotypes D-K?

Q. What Diseases are caused by serotypes L1-L3?

Answers:

Q. Why are chlamydiae Obligate intracellular parasites?

Because they can’t make their own ATP.

Q. What are 2 forms of Chlamydiae?

Elementary body (small , dense)

Infectious

Enters cell via Endocytosis .

Reticulate body

Replicates in cell by fission form seen on tissue culture.

Q. What is peculiar about Chlamydial cell wall?

It lacks muramic acid.

Q. How can chlamydiae be diagnosed in lab?

Cytoplasmic inclusions seen on Giemsa or fluorescent antibody-stained smear.

Q. What diseases are Caused by C. trachomatis?

Reactive arthritis, conjunctivitis, nongonococcal urethritis, and PID.

Q. What diseases are casued by C. pneumonia and C. pisttaci?

Atypical Pneumonia.

Q. How is Chlamydial infection treated?

Azithromycin (Single Dosing)

Doxycycline

Q. What dieases are caused by Serotypes A, B & C?

Chronic infection, cause blindness clue to follicular conjunctivitis in Africa. Common in Children.

Q. What diseases are caused by Serotypes D-K?

  • Urethritis/PID,
  • ectopic pregnancy,
  • neonatal pneumonia (staccato cough) ,
  • neonatal conjunctivitis.

Q. What Diseases are caused by serotypes L1-L3?

Lymphogranuloma Venereum

 

 

 
 
 

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